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Simulated Moving Bed(SMB)
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Simulated Moving Bed(SMB) HOME > RESEARCH > Simulated Moving Bed(SMB)
Simulated Moving Bed (SMB) chromatography is promising
process which is continuous chromatography like True Moving
Bed(TMB) chromatography using counter-current flow.
SMB process can provide some advantages such as high productivity, high efficiency
and low energy consumption. Also, SMB chromatography can be applied to the
separation of binary mixture. With these favorable characteristics of SMB, it is
evaluated positively in petrochemical, pharmaceutical, and fine chemical industries.
SMB research was investigated deeply in order to develop separation process in Korea.
Through this research, SMB process will be regarded as an important technology in
petrochemical and fine chemistry industries contributing to the production of high
value added materials.
Figure 1. Separation of Orange G and Bluedextran using SMB. We can see separtion process through color of two materials
Our lab has been successfully used for biological products such as organic acids, sugars, amino acids, and fatty
acids purification.
Lactic acid Phenylalanine and tryptophan
Xylitol and maltitol EPA and DHA
Fructo-oligosaccharide
Current researches of SMB :
L-Ribouse Purification by Simulated Moving Bed (SMB) Chromatography
Endotoxin Removal from Protein Solution
Ionic Liquid and Sugars Recovery from Hydrolzed Biomass Using SMB
Development of Modified SMB Process
Multi Component Separation Using SMB
Application of Thermal SMB Concentrator
Development of Simulated Moving Bed Reactor (SMBR) Process
Tacrolimus Separation Using SMB